abstract：:The importance of fibrinogen has been identified in two prospective observational studies. Reactive elevations in fibrinogen levels that occur within hours of a major stroke invalidate most cross-sectional case-control studies evaluating fibrinogen as a risk factor. However, as no elevation is seen following fresh epi...

journal_title：European heart journal

authors： Qizilbash N

更新日期：1995-03-01 00:00:00

abstract：UNLABELLED:To study the ablation effects induced by excimer laser coronary angioplasty (ELCA), we examined 41 segments of nine isolated coronary arteries. An electronic intracoronary ultrasound device (ICUS: 20 MHz, 3.5F, Endosonics) was positioned coaxially within the vessel. Angioplasty was performed using a 1.7 mm E...

journal_title：European heart journal

authors： Schmid KM,Xie D,Voelker W,Oberhoff M,Wehrmann M,Baumbach A,Haase KK,Karsch KR

更新日期：1995-02-01 00:00:00

abstract：:The aim of this study was to evaluate the effect of nadolol in modifying the standard deviation of RR intervals (SDRR) and the coefficient of variance (CV) in 47 patients characterized by symptomatic, frequent (> 30 h-1) and reproducible premature ventricular contractions (PVCs). Sixteen patients had suffered a previo...

journal_title：European heart journal

authors： Pitzalis MV,Mastropasqua F,Massari F,Totaro P,Passantino A,Rizzon P

更新日期：1995-02-01 00:00:00

abstract：:The objectives of this study were to assess the impact of the new 'Shahal' (pre-hospital cardiac service) on subscribers' 'decision time'. A professional 24-h mobile emergency cardiac service has been set up, monitored by intensive care nurses via a central computerized operation unit. All subscribers carry a cardiobe...

journal_title：European heart journal

authors： Roth A,Herling M,Vishlitzki V

更新日期：1995-01-01 00:00:00

abstract：:The purpose of this study was to describe the mechanism and determine predictive factors of mitral valve rupture requiring valve replacement following percutaneous mitral commissurotomy. Of the 350 consecutive patients treated by balloon mitral commissurotomy, the procedure was not completed in 16, and 11 developed ac...

journal_title：European heart journal

authors： Le Feuvre C,Bonan R,Rey MJ,Serra A,Leung TK,Petitclerc R,Leclerc Y,Creépeau J,Dyrda I

更新日期：1995-01-01 00:00:00

abstract：:Early treatment with ACE inhibitors of even moderate heart failure is clinically beneficial, even though haemodynamic measurements cannot adequately quantitate such improvement. Neurohumoral assessment is, however, supposed to be more accurate. In 55 patients with moderate heart failure (ejection fraction < or = 35%),...

journal_title：European heart journal

authors： Nussberger J,Fleck E,Bahrmann H,Delius W,Schultheiss HP,Brunner HR

更新日期：1994-12-01 00:00:00

abstract：:The alterations of the beta-adrenoceptor adenylyl cyclase are reviewed. In failing myocardium, the down-regulation of beta 1-adrenoceptors is accompanied by a decrease in steady state mRNA levels, as studied with quantitative polymerase chain reactions in dilated and ischaemic cardiomyopathy. The density of beta 2-adr...

journal_title：European heart journal

authors： Böhm M,Lohse MJ

更新日期：1994-12-01 00:00:00

abstract：:We studied the effects of angiotensin (Ang) I and II in a variety of isolated human cardiac tissues contracting under physiological conditions (37 degrees C, 60 beats.min-1). Ang I and II consistently increased the peak developed force of human atrial muscles by 30-40%, an effect that was completely blocked by 10(-6) ...

journal_title：European heart journal

authors： Holubarsch C,Schmidt-Schweda S,Knorr A,Duis J,Pieske B,Ruf T,Fasol R,Hasenfuss G,Just H

更新日期：1994-12-01 00:00:00

abstract：:The aim of our study was to examine if echocardiography can reproducibly be used in a multicentre study to select high risk patients with reduced left ventricular function early after an acute myocardial infarction (MI). In the TRAndolapril Cardiac Evaluation Study (TRACE) patients with reduced left ventricular systol...

journal_title：European heart journal

authors： Køber L,Torp-Pedersen C,Carlsen J,Videbaek R,Egeblad H

更新日期：1994-12-01 00:00:00

abstract：:Diastolic heart disease is common and appears to be the primary abnormality in a substantial proportion of all patients with CHF. The epidemiology and natural history of the condition appears different to that of systolic heart failure, resulting in significant morbidity although contributing little to overall mortali...

journal_title：European heart journal

authors： Wheeldon NM,Clarkson P,MacDonald TM

更新日期：1994-12-01 00:00:00

abstract：:Eight young healthy male subjects, members of a Himalayan expedition, underwent 24 h Holter monitoring before departure, after 1 and 4 weeks at high altitude (5000 m) and after return to sea level. At high altitude, the circadian reciprocal changes in low and high frequency (LF, HF) were absent, with no significant re...

journal_title：European heart journal

authors： Ponchia A,Noventa D,Bertaglia M,Carretta R,Zaccaria M,Miraglia G,Pascotto P,Buja G

更新日期：1994-11-01 00:00:00

abstract：UNLABELLED:Left atrial spontaneous echo contrast, detected by transoesophageal echocardiography in patients with non-valvular atrial fibrillation reflects slow blood flow and is associated with an increased risk of cardio-embolism. The purpose of this study was to find echo/Doppler predictors of left atrial spontaneous...

journal_title：European heart journal

authors： Pop GA,Meeder HJ,Roelandt JR,van Oudenaarden W,Bulens C,Verweij W,Gijsbers C,van Domburg R,Koudstaal PJ

更新日期：1994-11-01 00:00:00

abstract：:The aim of the present investigation was to evaluate the type and the incidence of cardiac arrhythmias and ischaemic events in patients suffering from testicular cancer and submitted to combination chemotherapy with cisplatin, bleomycin and vinblastine (PVB) or etoposide (PEB). Forty-seven patients took part in the st...

journal_title：European heart journal

authors： Villani F,Misrachi D,Galimberti M

更新日期：1994-11-01 00:00:00

abstract：:The haemodynamic effects on the peripheral vascular bed of L-acetylcarnitine, L-propionylcarnitine, and nitroglycerin were tested by echo-Doppler in a double blind cross-over study. Eleven male patients suffering from peripheral arterial obliterative disease (PAOD) in the second stage of Fontaine's classification, and...

journal_title：European heart journal

authors： Sabbá C,Berardi E,Antonica G,Ferraioli G,Buonamico P,Godi L,Brevetti G,Albano O

更新日期：1994-10-01 00:00:00

abstract：:In atrial flutter, chemical conversion with class I drugs is often unsuccessful, whereas class III drugs seem more promising. The different electrophysiological effects of these drugs may explain this discrepancy. To date, only experimental data show the differential effects of these drugs on conversion rate and atria...

journal_title：European heart journal

authors： Crijns HJ,Van Gelder IC,Kingma JH,Dunselman PH,Gosselink AT,Lie KI

更新日期：1994-10-01 00:00:00

abstract：:The duration of the reduction of mortality after coronary artery bypass grafting (CABG) is an important issue and this study was undertaken to evaluate time in relation to excess mortality among CABG patients compared with the general population. Survival was analysed in 4661 patients who had undergone their first iso...

journal_title：European heart journal

authors： Ståhle E,Bergström R,Holmberg L,Edlund B,Nyström SO,Sjögren I,Hansson HE

更新日期：1994-09-01 00:00:00

abstract：:The efficacy and safety of a single infusion of cibenzoline, a class I antiarrhythmic drug, were assessed in 86 patients presenting with a supraventricular tachyarrhythmia following heart surgery in a placebo-controlled double-blind parallel study. Cibenzoline was effective in 13 patients (30%) vs three patients (6.9%...

journal_title：European heart journal

authors： Ollitrault J,Quilliet L,Scheck F,Lelong B,Richard A,Jarry G,Guize L

更新日期：1994-09-01 00:00:00

abstract：:Reactive thrombocytosis following cardiopulmonary bypass surgery is generally considered to be a benign condition which is transient and does not require specific therapy. We describe three patients who developed stroke in association with reactive thrombocytosis in the late recovery period following cardiopulmonary b...

journal_title：European heart journal

authors： Crowley JJ,Hannigan M,Daly K

更新日期：1994-08-01 00:00:00

abstract：:Orally active angiotensin converting enzyme (ACE) inhibitors have been successfully used in the treatment of congestive heart failure and hypertension. However, adverse skin reactions, such as angioneurotic oedema have been reported following such medication. Furthermore, these drugs have been associated with a persis...

journal_title：European heart journal

authors： Andersson RG,Persson K

更新日期：1994-08-01 00:00:00

abstract：:The study of 'atrial vulnerability' is often clinically indicated but it requires the use of invasive intracardiac stimulation. The purpose of the study was to assess the use of oesophageal pacing in the evaluation of atrial tachyarrhythmias (ATA). Fifty-five patients with documented ATA (group I) and 60 without (grou...

journal_title：European heart journal

authors： Brembilla-Perrot B

更新日期：1994-08-01 00:00:00

abstract：:The study was designed to examine the safety and efficacy of acute interventional use of captopril on left ventricular volumes, ventricular arrhythmias and neurohormones during thrombolysis in patients with a first anterior myocardial infarction, within 6 h of onset of symptoms. Left ventricular dysfunction and progno...

journal_title：European heart journal

authors： Kingma JH,van Gilst WH,Peels CH,Dambrink JH,Verheugt FW,Wielenga RP

更新日期：1994-07-01 00:00:00

abstract：:The feasibility of transcatheter laser coagulation of atrial myocardium was tested in a canine model by using a combined electrode-laser catheter. In 17 anaesthetized beagles a total of 264 lesions, 12-19 per dog, and 3-5 in each area were produced in: (1) the lateral walls, (2) the posterior right atrial walls, (3) t...

journal_title：European heart journal

authors： Weber HP,Heinze A,Enders S,Ruprecht L,Unsöld E

更新日期：1994-07-01 00:00:00

abstract：:The early termination of clinical trials, for either benefit or harm, often generates undue enthusiasm or alarm. The enhanced publicity attending early termination of a trial promotes inappropriate interpretations because of the inherent difficulty of a prompt and comprehensive data review. Furthermore, the process of...

journal_title：European heart journal

authors：

更新日期：1994-06-01 00:00:00

abstract：:Spinal cord electrical stimulation is an alternative therapy for patients with chronic pain syndromes including angina. Although it has been shown to produce symptomatic relief and reduce ischaemia, doubts remain about its long-term safety. We report here for the first time the results of a follow-up study over a peri...

journal_title：European heart journal

authors： Sanderson JE,Ibrahim B,Waterhouse D,Palmer RB

更新日期：1994-06-01 00:00:00

abstract：:We now have conclusive data that ACE inhibitors reduce mortality, morbidity, and symptoms in patients with low ejection fraction and/or heart failure. Therefore, ACE inhibitors should be routinely used in all such patients, as long as there are no clear contraindications. Routine use of ACE inhibitors will lead to pro...

journal_title：European heart journal

authors： McKelvie R,McConachie D,Yusuf S

更新日期：1994-05-01 00:00:00

abstract：:The slope and pressure half-time of the aortic regurgitant velocity spectrum have been used as non-invasive markers of regurgitant severity. Recent in vitro and theoretical work, however, has suggested a confounding effect of systemic vascular resistance and left ventricular compliance on these parameters. To study th...

journal_title：European heart journal

authors： Griffin BP,Flachskampf FA,Reimold SC,Lee RT,Thomas JD

更新日期：1994-05-01 00:00:00

abstract：:Plasma neuropeptide Y-like immunoreactivity (NPY-LI) is elevated in patients with acute myocardial ischaemia and congestive heart failure (CHF) owing to increased activity of the sympathetic nervous system. The prognostic value of plasma NPY-LI with regard to mortality was studied in 324 random patients admitted to a ...

journal_title：European heart journal

authors： Ullman B,Hulting J,Lundberg JM

更新日期：1994-04-01 00:00:00

abstract：:In this study, the acute haemodynamic effects of angiotensin converting enzyme (ACE) inhibition with intravenous enalaprilat alone or in combination with preload restoration were determined in patients with severe heart failure complicating acute myocardial infarction. Ten patients with raised pulmonary arterial wedge...

journal_title：European heart journal

authors： Tohmo H,Karanko M,Korpilahti K

更新日期：1994-04-01 00:00:00

abstract：:Left ventricular flow patterns were studied at rest by colour flow Doppler echocardiography in 33 patients with mitral tilting-disc prostheses (group 1), in 38 patients with mitral tissue prostheses (group 2) and in 18 healthy volunteers (controls). A 'crossed' flow pattern was seen in 14 patients with mechanical (42%...

journal_title：European heart journal

authors： Maire R,Ikram S,Odemuyiwa O,Groves PH,Lo SV,Banning AP,Hall RJ

更新日期：1994-03-01 00:00:00

abstract：:Cardiac output was measured in 11 patients undergoing routine cardiac catheterization using a carbon dioxide rebreathing technique and compared with cardiac output measured by direct Fick and thermodilution. The carbon dioxide rebreathing technique gave consistently lower values for cardiac output than the other two m...

journal_title：European heart journal

authors： Nugent AM,McParland J,McEneaney DJ,Steele I,Campbell NP,Stanford CF,Nicholls DP

更新日期：1994-03-01 00:00:00

abstract：:An 83-year-old man was hospitalized due to general fatigue and dyspnoea. He was diagnosed as having complete atrioventricular (AV) block due to cardiac involvement by a malignant lymphoma. Eleven days after the initiation of chemotherapy, the complete AV block disappeared and only a first degree AV block remained. ...

journal_title：European heart journal

authors： Otsuji Y,Arima N,Fujiwara H,Saito K,Kisanuki A,Tanaka H

更新日期：1994-03-01 00:00:00

abstract：:The efficacy and safety of catheter ablation of accessory pathways (AP) was studied in 79 children (age, 4-16 years), using DC shocks (n = 25) or radiofrequency energy (n = 54). All patients had documented arrhythmias including ventricular fibrillation in four. Organic heart disease was present in four patients. AP lo...

journal_title：European heart journal

authors： Haissaguerre M,Puel V,Bekheit S,Fisher B,Dartigues JF,Egloff P,Le Metayer P,Clementy J,Warin JF

更新日期：1994-02-01 00:00:00

abstract：:The prognostic significance of angina pectoris and the effect of intervention with verapamil on the incidence of angina pectoris were studied in patients recovering from myocardial infarction and included in the Danish Verapamil Infarction Trial II. During the second week after admission patients were doubly-blindly r...

journal_title：European heart journal

authors： Jespersen CM,Hansen JF,Mortensen LS

更新日期：1994-02-01 00:00:00

abstract：:Organic nitrates exert their effect by direct inhibition of vascular tone, resulting in decreased myocardial oxygen demand and improved oxygen supply. Less well known is the effect of nitrates on blood rheology. To evaluate the haemodiluting effect of intravenous nitroglycerin we studied 70 consecutive patients admitt...

journal_title：European heart journal

authors： Arend SM,Bax JJ,Hermans J,van der Wall EE,Sedney MI

更新日期：1994-01-01 00:00:00

abstract：:Some studies provide a link between the width of QRS complexes and late potentials occurring at the end of the QRS complex in signal-averaged recordings. The purpose of this study was to compare three methods of QRS duration measurement: the conventional 12 lead ECG, the Frank vectorcardiogram (VCG) and the signal-ave...

journal_title：European heart journal

authors： Brembilla-Perrot B

更新日期：1994-01-01 00:00:00

abstract：:It is not yet clear whether 99mTc-methoxyisobutyl-isonitrile (MIBI)-uptake is a reliable indicator of myocardial viability, and a threshold value, differentiating viable from scarred myocardium, in comparison to a morphological and functional standard of reference has not been defined. MIBI-uptake was quantified in 80...

journal_title：European heart journal

authors： Baer FM,Smolarz K,Theissen P,Voth E,Schicha H,Sechtem U

更新日期：1994-01-01 00:00:00

abstract：:During the long-term follow-up of patients with hypertrophic cardiomyopathy (HCM), some patients develop left ventricular (LV) wall motion abnormalities in the absence of fixed coronary artery disease. The purpose of this study is to clarify which clinical features in patients with HCM seem to influence gradual develo...

journal_title：European heart journal

authors： Ishiwata S,Nishiyama S,Nakanishi S,Seki A

更新日期：1993-12-01 00:00:00

abstract：:We have previously shown that transdermal nitroglycerin may induce an increase in the activity of the adrenergic and the renin-angiotensin-aldosterone systems (SRAA) in patients with chronic stable angina pectoris (SA); when the activation of these systems is more pronounced, the antianginal effect of this drug seems ...

journal_title：European heart journal

authors： Muiesan ML,Boni E,Castellano M,Beschi M,Cefis G,Cerri B,Verdecchia P,Porcellati C,Pollavini G,Agabiti-Rosei E

更新日期：1993-12-01 00:00:00

abstract：:Recent studies have illustrated that in addition to the well known risk factors, such as lipoproteins, smoking, hypertension, there are others that cause atherosclerosis and myocardial infarction. Our knowledge of atherosclerotic lesions has increased. We now know that atherosclerotic changes are due to inflammatory c...

journal_title：European heart journal

authors： Nieminen MS,Mattila K,Valtonen V

更新日期：1993-12-01 00:00:00

abstract：:The antibody prevalence data indicate that C. pneumoniae infections are common worldwide and more frequently occur in middle-aged and elderly males than in females. C. pneumoniae infections are first acquired in childhood in heavily populated areas, whereas in northern countries, first infections are generally at teen...

journal_title：European heart journal

authors： Leinonen M

更新日期：1993-12-01 00:00:00